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Endocannabinoids mediate neuron-astrocyte communication

Over the last decades, however, this view changed dramatically. A variety of specific roles have been assigned to different types of glial cells.

Mar 27, 2008 · Endocannabinoids mediate neuron-astrocyte communication. These results demonstrate the existence of endocannabinoid-mediated neuron-astrocyte communication, revealing that astrocytes are targets of cannabinoids and might therefore participate in the physiology of cannabinoid-related addiction. They also reveal the existence of an Endocannabinoids Mediate Neuron-Astrocyte Communication ... Mar 27, 2008 · Cannabinoid receptors play key roles in brain function, and cannabinoid effects in brain physiology and drug-related behavior are thought to be mediated by receptors present in neurons. Neuron-astrocyte communication relies on the expression by astrocytes of neurotransmitter receptors. Yet, the expression of cannabinoid receptors by astrocytes in situ and their involvement in the neuron Endocannabinoids Mediate Neuron-Astrocyte Communication ... Considering recent data demonstrating the relevance of neuron-astrocyte communication in brain physiology (Araque et al., 2001, Haydon, 2001, Haydon and Carmignoto, 2006, Nedergaard et al., 2003, Perea and Araque, 2007, Volterra and Meldolesi, 2005), whether endocannabinoid signaling between neurons and astrocytes is involved in these processes Endocannabinoids Mediate Neuron-Astrocyte Communication ...

Endocannabinoids Mediate Neuron-Astrocyte Communication

A variety of specific roles have been assigned to different types of glial cells. Astrocytes constitute the link of the vascular system and neighboring neurons. Endocannabinoid signaling modulates neurons of the ...

May 10, 2012 · Nevertheless, present study shows that the basic principles of the neuron–astrocyte communication previously described in animal models, that is, astrocyte responsiveness to synaptic activity and astrocyte ability to release gliotransmitters that act on neurons, exist in human brain. Endocannabinoids mediate neuron-astrocyte communication

Jan 07, 2015 · Endocannabinoids primarily influence neuronal synaptic communication within the nervous system. To exert their function, endocannabinoids need to travel across the intercellular space. However, how hydrophobic endocannabinoids cross cell membranes and move extracellularly remains an unresolved problem.

Endocannabinoids mediate neuron-astrocyte Communicationmore. by Marta Navarrete. Download (.pdf). Save to Library. 116 Views. •. Mechanism and Kinetics How the different forms of endocannabinoid-mediated plasticity are "Neuron- Astrocyte Communication Mediated by Endocannabinoids in Health and Disease astrocytes in situ express functional CB1Rs that mediate relevant effects on astrocyte–neuron communication and synaptic modulation.

Araque, A. (2008) Endocannabinoids mediate neuron–astrocyte communication.

Roles of other types of glia, including white matter glia, microglia, and polydendrocytes are not discussed and we refer the reader to other recent review articles [4, 5, 6]. (PDF) Astrocytes in endocannabinoid signalling Astrocytes in endocannabinoid signalling. Endocannabinoids released by neurons elevate calcium and stimula te glutamate release in astr ocytes. (a) mediate neuron– astrocyte communication.

Studies in cell culture and brain slices have shown that a number of different pathways potentially participate in … Synaptic Plasticity and Astrocyte-Neuron Interations Navarrete M and Araque A. 2008 Endocannabinoids mediate neuron-astrocyte Communication. Neuron, 57:883-893. Rangel C, Navarrete M, Corchado JC, Espinosa-García J. 2006 Potential energy surface, kinetics, and dynamics study of the Cl + CH4 → HCl + CH3 reaction. J Chem Phys, 124:124306.

These results demonstrate the existence of endocannabinoid-mediated neuron-astrocyte communication, revealing that astrocytes are targets of cannabinoids and might therefore participate in the physiology of cannabinoid-related addiction. They also reveal the existence of an Endocannabinoids Mediate Neuron-Astrocyte Communication ... Mar 27, 2008 · Cannabinoid receptors play key roles in brain function, and cannabinoid effects in brain physiology and drug-related behavior are thought to be mediated by receptors present in neurons. Neuron-astrocyte communication relies on the expression by astrocytes of neurotransmitter receptors. Yet, the expression of cannabinoid receptors by astrocytes in situ and their involvement in the neuron Endocannabinoids Mediate Neuron-Astrocyte Communication ... Considering recent data demonstrating the relevance of neuron-astrocyte communication in brain physiology (Araque et al., 2001, Haydon, 2001, Haydon and Carmignoto, 2006, Nedergaard et al., 2003, Perea and Araque, 2007, Volterra and Meldolesi, 2005), whether endocannabinoid signaling between neurons and astrocytes is involved in these processes Endocannabinoids Mediate Neuron-Astrocyte Communication ...

However, the consequences of the endocannabinoid-mediated neuron-astrocyte signaling on synaptic transmission are unknown. We show that endocannabinoids released by hippocampal pyramidal neurons increase the probability of … Endocannabinoids Mediate Neuron-Astrocyte Communication Endocannabinoids Mediate Neuron-Astrocyte Communication Astrocytes in endocannabinoid signalling Oct 19, 2014 · Endocannabinoid signalling in neuron–astrocyte communication For years, the existence and role of CB1Rs in astrocytes has been a controversial issue. Earlier studies showed discrepancies in the expression of CB1Rs by astrocytes in culture (see [ 30 ]), which could arise from the well-known phenotypic changes in astrocytes in different culture Endocannabinoids Mediate Neuron-Astrocyte Communication Neuron-astrocyte communication relies on the expression by astrocytes of neurotransmitter receptors. Yet, the expression of cannabinoid receptors by astrocytes in situ and their involvement in the neuron-astrocyte communication remain largely unknown. Endocannabinoids Mediate Neuron-Astrocyte Communication - … Endocannabinoids Mediate Neuron-Astrocyte Communication .